Publications related to Answer ALS, a project ALS FAC helped fund

1. Baxi, E. G. et al. Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines. Nat Neurosci 1-12 (2022) doi:10.1038/s41593-021-01006-0.

2. Zhang, S. et al. Genome-wide identification of the genetic basis of amyotrophic lateral sclerosisNeuron (2022) doi:10.1016/j.neuron.2021.12.019.

3. Gilley, J. et al. Enrichment of SARM1 alleles encoding variants with constitutively hyperactive NADase in patients with ALS and other motor nerve disorders. Medrxiv 2021.06.17.21258268 (2021) doi:10.1101/2021.06.17.21258268.

4. Ramamoorthy, D. et al. Identifying Patterns of ALS Progression from Sparse Longitudinal DataMedrxiv 2021.05.13.21254848 (2021) doi:10.1101/2021.05.13.21254848.

5. Coyne, A. N. et al. Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALSSci Transl Med 13, eabe1923 (2021).

6. Coyne, A. N. & Rothstein, J. D. Nuclear lamina invaginations are not a pathological feature of C9orf72 ALS/FTDActa Neuropathologica Commun 9, 45 (2021).

7. Coyne, A. N. & Rothstein, J. D. The ESCRT-III protein VPS4, but not CHMP4B or CHMP2B, is pathologically increased in familial and sporadic ALS neuronal nucleiActa Neuropathologica Commun 9, 127 (2021).

8. Course, M. M. et al. Evolution of a Human-Specific Tandem Repeat Associated with ALS. Am J Hum Genetics 107, 445–460 (2020).

9. Agurto, C. et al. Analyzing progression of motor and speech impairment in ALS2019 41st Annu Int Conf Ieee Eng Medicine Biology Soc Embc 00, 6097–6102 (2019).

10. Nicolas, A. et al. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron 97, 1268-1283.e6 (2018).