News – ALS Finding a Cure®

ALS Finding a Cure Call for Proposals – From Resilience to Vulnerability: Defining the Biological Determinants of ALS Onset

Justin Green2026-03-02T19:08:53+00:00

ALS Finding a Cure® Request for Proposals (RFP) From Resilience to Vulnerability: Defining the Biological Determinants of ALS Onset Overview ALS Finding a Cure® (ALSFAC) invites proposals for research aimed at defining the biological mechanisms that determine why ALS develops in some individuals but not others. This initiative will support mechanistic studies that investigate determinants of motor neuron vulnerability, pathways that confer resistance to neurodegeneration, and biological events that initiate ALS prior to clinical symptom onset. Projects may include laboratory-based, computational, and human-focused research using model systems, biospecimens, datasets, or clinical populations. Background and Rationale Amyotrophic lateral sclerosis [...]

ALS Finding a Cure Call for Proposals – From Resilience to Vulnerability: Defining the Biological Determinants of ALS OnsetJustin Green2026-03-02T19:08:53+00:00

2025 Advancing ALS Discovery through Artificial Intelligence and Natural Language Processing
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2025 Advancing ALS Discovery through Artificial Intelligence and Natural Language Processing

Justin Green2026-02-28T00:00:10+00:00

ALS Finding a Cure, ALS Network, and Hop On A Cure Award Research Grants to Four Teams of Leading Scientists Advancing Artificial Intelligence and Natural Language Processing in ALS Discovery Overview: ALS is a serious neurodegenerative disease with need for more therapeutic options. AI and Natural Language Processing offer the potential to revolutionize ALS research by enabling the extraction of meaningful insights from complex datasets, including electronic health records (EHRs), published medical literature, clinical trial data, omics datasets, and real-world patient-reported data. ALS Finding a Cure recently issued a grant call for proposals with the following goals: Drug Discovery and Repurposing [...]

2025 Advancing ALS Discovery through Artificial Intelligence and Natural Language ProcessingJustin Green2026-02-28T00:00:10+00:00

2025: ALS Finding a Cure Request for Proposals

Justin Green2026-02-27T23:39:52+00:00

2025: ALS Finding a Cure Request for Proposals Advancing ALS Discovery through Artificial Intelligence and Natural Language Processing Overview: ALS Finding a Cure® is pleased to announce a Request for Proposals (RFP) to support innovative research projects leveraging Artificial Intelligence (AI) and Natural Language Processing (NLP) to advance ALS discovery. This funding opportunity seeks to catalyze transformative research that integrates AI-driven methodologies to improve diagnosis, biomarker identification, disease progression modeling, and therapeutic target discovery in ALS. Background: ALS is a devastating neurodegenerative disease with no cure and limited therapeutic options. AI and NLP offer the potential to revolutionize [...]

2025: ALS Finding a Cure Request for ProposalsJustin Green2026-02-27T23:39:52+00:00

ALS ONE – United in ALS Research, Care, and Community
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ALS ONE – United in ALS Research, Care, and Community

Justin Green2026-02-28T00:03:56+00:00

ALS ONE - United in ALS Research, Care, and Community Our Pals for pALS Community Connect Program One of the greatest wishes of our founder, Kevin Gosnell, after launching ALS ONE and united research and care—and before losing his battle to ALS just 14 months after his diagnosis—was to build a compassionate, connected community for those impacted by the disease. He envisioned a network where individuals living with ALS, those who had lost loved ones, and supporters could come together to uplift one another, easing the journey with shared understanding, support, and even moments of joy. Our Pals [...]

ALS ONE – United in ALS Research, Care, and CommunityJustin Green2026-02-28T00:03:56+00:00

Hope Loves Company
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Hope Loves Company

Justin Green2026-02-28T00:02:44+00:00

Hope Loves Company Hope Loves Company (HLC) is a nationally recognized nonprofit that provides support, resources and community to children who have or had a loved one with ALS. We give children and young adult caregivers the tools they need to navigate grief, find joy, and remain hopeful. Recognizing a gap in support services for young caregivers, Jodi O'Donnell Ames founded HLC to provide critical emotional and educational resources for children and young adults. HLC's focus is to offer mental health and educational support and caregiving resources through free, year-round, nationwide programs, including Camp HLC, Hugs of Hope, [...]

Hope Loves CompanyJustin Green2026-02-28T00:02:44+00:00

2024 ALS Organoid Program Information
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2024 ALS Organoid Program Information

Justin Green2026-02-28T00:04:38+00:00

2024 ALS Organoid Program Information Overview: Organoids are a powerful new and compelling technology for studying disease biology. Several different and complementary organoid models currently exist with relevance to ALS, but none of these models has been tested across multiple ALS iPSC lines, and all have been created using different lines/genetic backgrounds making comparisons between/among them challenging. The reagents and assays used to assess ALS phenotypes have likewise varied. This variability and limited scale make it challenging to interpret results and to establish methodologic robustness. ALS Finding a Cure recently issued a grant call for proposals with the following goals: To [...]

2024 ALS Organoid Program InformationJustin Green2026-02-28T00:04:38+00:00

ALSFAC and Hop On A Cure Partner to fund 5 Investigators in a new ALS Organoid Program
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ALSFAC and Hop On A Cure Partner to fund 5 Investigators in a new ALS Organoid Program

Justin Green2024-09-30T17:53:00+00:00

ALSFAC and Hop On A Cure Partner to fund 5 Investigators in a new ALS Organoid Program ALS Finding a Cure and Hop On A Cure announce their partnership to award $1.5M in grant funding for 2-year awards designed to advance the application of organoid technology for use in ALS translational research and development. Organoids are a powerful new and compelling technology for studying disease biology. Several different and complementary organoid models currently exist with relevance to ALS, but none of these models has been tested across multiple ALS iPSC lines, and all have been created using different lines/genetic [...]

ALSFAC and Hop On A Cure Partner to fund 5 Investigators in a new ALS Organoid ProgramJustin Green2024-09-30T17:53:00+00:00

Compassionate Care ALS (CCALS)

Anne D Pham2026-02-27T23:58:38+00:00

Compassionate Care ALS (CCALS) Compassionate Care ALS (CCALS), a nonprofit located in Falmouth, Massachusetts, currently works with more than 1,050 ALS families in 47 states and multiple foreign countries. Funding from ALSFAC WE CARE will allow CCALS to grow its staff to serve more ALS patients their families, communities, and healthcare providers. We will provide resources including equipment, educational opportunities, Medicare/Medicaid assistance, communication assistance, guidance and awareness with regards to living with ALS, caregiving, and exploring end-of-life when invited, all at no cost to families across the United States.

Compassionate Care ALS (CCALS)Anne D Pham2026-02-27T23:58:38+00:00

ALS Ride for Life: Mobility Matters Program

Anne D Pham2026-02-27T23:58:49+00:00

ALS Ride for Life: Mobility Matters Program As a patient-driven, primarily volunteer organization, the mission of ALS Ride For Life is to serve the ALS community by assisting patients and their families through a variety of supportive services to ease the financial and emotional stress this disease places on families, raising research funds to find a cure, raising public awareness, and providing the community with the latest ALS news, information, and inspiration. With a minimal staff (the equivalent of 2 employees), an active board of directors, and a team of volunteers. To apply for our Mobility Matters Program or [...]

ALS Ride for Life: Mobility Matters ProgramAnne D Pham2026-02-27T23:58:49+00:00

ALS Finding a Cure Request for Proposals
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ALS Finding a Cure Request for Proposals

Anne D Pham2024-01-09T20:06:17+00:00

ALS Finding a Cure Request for Proposals To Develop and Validate ALS Organoid Models Overview: Organoids are a powerful new and compelling technology for studying disease biology. Several different and complementary organoid models currently exist with relevance to ALS, but none of these models has been tested across multiple ALS iPSC lines, and all have been created using different lines/genetic backgrounds making comparisons between/among them challenging. The reagents and assays used to assess ALS phenotypes have likewise varied. This variability and limited scale make it challenging to interpret results and to establish methodologic robustness. This targeted RFP aims to [...]

ALS Finding a Cure Request for ProposalsAnne D Pham2024-01-09T20:06:17+00:00